Levy JA, Marchand M, Iorio L, Cassini W, Zahalsky MP. Intracavernous injections of bone marrow mononucleated cells for postradical prostatectomy erectile dysfunction: final results of the INSTIN clinical trial. Yiou R, Hamidou L, Birebent B, Bitari D, Le Corvoisier P, Contremoulins I, et al. Hyperbaric oxygen can induce angiogenesis and recover erectile function. Hadanny A, Lang E, Copel L, Meir O, Bechor Y, Fishlev G, et al. Phase I and registry study of autologous bone marrow concentrate evaluated in PDE5 inhibitor refractory erectile dysfunction. 2008 20:370–7.īieri M, Said E, Antonini G, Dickerson D, Tuma J, Bartlett CE, et al. Assessment of endothelial function in the patient with erectile dysfunction: an opportunity for the urologist. Erection hardness score for the evaluation of erectile dysfunction: further psychometric assessment in patients treated by intracavernous prostaglandins injections after radical prostatectomy.
Parisot J, Yiou R, Salomon L, de la Taille A, Lingombet O, Audureau E. The sexual health inventory for men (IIEF-5). The International Index of Erectile Function (IIEF): a state-of-the-science review. The efficacy of penile duplex ultrasound in erectile dysfunction management decision-making: a systematic review. Nashed A, Lokeshwar SD, Frech F, Mann U, Patel P. Energy-based therapies for erectile dysfunction: current and future directions. A systematic review of human trials using stem cell therapy for erectile dysfunction.
Lokeshwar SD, Patel P, Shah SM, Ramasamy R. Alternative treatment for erectile dysfunction: a growing arsenal in men’s health. Muncey W, Sellke N, Kim T, Mishra K, Thirumavalavan N, Loeb A, et al. Restorative therapies for erectile dysfunction: position statement from the Sexual Medicine Society of North America (SMSNA). Liu JL, Chu KY, Gabrielson AT, Wang R, Trost L, Broderick G, et al. Clinically relevant effectiveness of focused extracorporeal shock wave therapy in the treatment of chronic plantar fasciitis: a randomized, controlled multicenter study. Gollwitzer H, Saxena A, DiDomenico LA, Galli L, Bouche RT, Caminear DS, et al. A 12-month follow-up after a single intracavernous injection of autologous adipose-derived regenerative cells in patients with erectile dysfunction following radical prostatectomy: an open-label phase I clinical trial. Haahr MK, Harken Jensen C, Toyserkani N, Andersen DC, Damkier P, Sorensen JA, et al. Safety and potential therapeutic effect of two intracavernous autologous bone marrow derived mesenchymal stem cells injections in diabetic patients with erectile dysfunction: an open label phase I clinical trial. 2021 18:926–35.Īl Demour S, Jafar H, Adwan S, AlSharif A, Alhawari H, Alrabadi A, et al. Platelet-rich plasma (PRP) improves erectile function: a double-blind, randomized, placebo-controlled clinical trial. Poulios E, Mykoniatis I, Pyrgidis N, Zilotis F, Kapoteli P, Kotsiris D, et al. Extracorporeal shockwave therapy in the treatment of erectile dysfunction: a prospective, randomized, double-blinded, placebo controlled study. Assessment scales for sexual disorders-a review. Current diagnosis and management of erectile dysfunction.
CRIFT 2015 DEEP THERAPY UPDATE
Epidemiology update of erectile dysfunction in eight countries with high burden. Goldstein I, Goren A, Li VW, Tang WY, Hassan TA.
Association of sexual problems with social, psychological, and physical problems in men and women: a cross sectional population survey.
CRIFT 2015 DEEP THERAPY TRIAL
These results provide a basis for the design of future clinical trials to improve the quality of trial data and aid in the development of standardized criteria for erectile dysfunction clinical trials.Ĭonsensus development conference statement. Subjective measures of erectile function were commonly reported, but definitions of inclusion criteria and objective outcome measures were inconsistent. We found substantial heterogeneity in methodological approach in the trials. Thirty (31.6%) trials had been completed yet only 3 (3.2%) have published results. The most common efficacy endpoint was International Index of Erectile Function and Sexual Health Inventory for Men, and only 29.5% utilized penile Doppler.
Only 41.1% of the trials evaluated safety. We identified 95 trials investigating energy-based/shockwave therapies (60/95), stem cell therapies (25/95), platelet-based therapies (6/95), and others (4/95). We evaluated trials initiated between 20 which listed a restorative therapy intervention. Data was extracted from on trials which contained the keywords “erectile dysfunction”. Our objective was to analyze methodological approaches and outcome measures of clinical trials evaluating restorative therapies for erectile dysfunction. Given the lack of regulatory approval for restorative therapies for the treatment of erectile dysfunction, we hypothesized that clinical trials would vary in methodology and endpoint measurements.
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